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doi: 10.1053/j.gastro.2007.04.007 [DOI] [PubMed] [Google Scholar] 97

Clinical trials show that even at this modest starting point, many patients experience meaningful appetite reduction and improved meal satisfaction within the first few weeks

Sweeteners such as sorbitol or sucralose might have a similar effect

You do get peaks and troughs, so some people get big effects right in the beginning, and it starts to taper off towards the end of the week
Study period 1/1/2021 to 10/1/2024 with follow-up possible through 7/1/2025 Study population: inclusion Patients with: PCOS (encounter or billing diagnosis with ICD-10-CM code E28.2) before exposure or within two years of drug trial start Evaluated sex of female or ambiguous Aged 18 to 50 at drug trial start No overlap in metformin and GLP-1 use At least one measurement within one year prior to trial start At least one measurement 9 to 15 months after trial start At least 70% of days covered by their exposure medication dispense Study population: exclusion Patients with: Evidence of pregnancy during baseline or outcome measurements Definitive pregnancy start date: Between 12 months before the first reading through the follow-up reading Definitive pregnancy end date, delivery, or if its ambiguous what point in the pregnancy the patient would be at (e.g

Studies suggest that hair loss affects approximately 1 in 20 people taking GLP-1 medications, and while it is often temporary, it can be deeply distressing
