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This data proves valuable for practitioners managing patients who frequently discuss medication tolerability concerns on platforms like Reddit, specifically for those who are non-responders to GLP-1

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2) insulin resistance leading to decreased glucose uptake by peripheral tissues (i.e., muscle and adipose)

The incorporation of high-cost medications without generic or biosimilar alternatives compromises already scarce resources, forcing difficult choices in public policy

Insulin resistance, de novo lipogenesis, and dysregulated blood glucose are key hallmarks in the progression of NAFLD as part of the multiple-hit hypothesis (39)

In patients with obesity undergoing sleeve gastrectomy, liraglutide has been explored for preoperative management, showing more pronounced effects in females by reducing inflammation and adhesion formation (63)