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Journal of Clinical Investigation

Research purposes only

What makes tirzepatide unit conversion particularly tricky is that compounded vials come in different concentrations

Semaglutide is now well known as the active ingredient in Novo Nordisks blockbuster type 2 diabetes drug Ozempic and weight-loss drug Wegovy, which were approved by the US Food and Drug Administration in 2017 and 2021, respectively

The results from the SURMOUNT-5 study are as follows: In the trial, participants were given either the maximum tolerated dose of tirzepatide (10 mg or 15 mg) or what was the maximum tolerated dose of semaglutide at the time (1.7 mg or 2.4 mg)