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who should not take glp 1 receptor agonists Trends in the Development of GLP-1 GLP-1 Drug Savings: A Complete
Description
doi: 10.1111/dom.14496 [DOI] [PubMed] [Google Scholar] 32.Hviid AVR, Srensen CM

Bit of Background These new classes of antiobesity medications (ie, the GLP-1 agonists and dual agonists), referred to in this article as weight management medications, arent really new.1-4 The basic science and pharmaceutical research and development to bring these to market began more than two decades ago when two scientists, Matthias Tschop, MD, and Richard DiMarchi, PhD, hypothesized that the actions of various gut hormones may offer safe and unprecedented weight loss

10.1038/ijo.2014.153 78 QiQ.ZhangH.JinZ.WangC.XiaM.ChenB.et al (2024)

The study also revealed new potential risks involving the pancreas and kidneys

What matters is not only the headline payout but also the underlying mechanics: return-to-player ranges, volatility, and promotional calendars
To balance risks and benefits, expert opinions emphasize the importance of individualized dosing, shared decision-making, and careful patient selection
