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In future trials, cerebrospinal fluid levels of -synuclein oligomers and pro-inflammatory cytokines such as IL-6 and TNF- may serve as biomarkers of both neurodegeneration and treatment response in PD, potentially reflecting disease-modifying effects through reduced protein aggregation and neuroinflammation

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On GLP-1 medications, it becomes even more critical because your overall food intake is reduced, which means you need to be strategic about what you eat when you do eat

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10.2337/dc15-1707 49

After that, if tolerated and under the supervision of your prescriber, the dose can be slowly increased up to 2.4 mg once a week
