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We identified that GLP-1R agonism reduced ethanol consumption, mitigated ethanol-induced upregulation of several liver metabolizing enzymes, including Cyp2e1 and also reduced Cyp2e1 independent of ethanol intake

But how do GLP-1s actually work

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The cost of generic GLP-1s is half that of brands

Cigna will stop covering GLP-1 weight-loss drugs such as Wegovy and Zepbound for its employees starting July 1, signaling that even major healthcare companies are struggling with the high cost of these medications

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