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[13] Wharton S, Haase CL, Kamran E, Liu A, Mancini J, Neish D, Pakseresht A, Power GS, Christensen RAG

GLP-1 receptor agonists, already used for Type 2 diabetes and obesity, show promise in reducing alcohol and drug-seeking behaviors through central reward and dopamine-related pathways

Retatrutide: The Triple-Action Contender Retatrutide, on the other hand, uses a triple-hormone mechanism, acting on GLP-1, GIP, and glucagon receptors

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2025;44(1):200

This article summarizes GPCR targets and pipelines highlighted by AstraZeneca, Pfizer, and Eli Lilly at JP Morgan Healthcare Conference 2024.