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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

GLP-1 constipation results from the drug's effect on gut motility, by slowing gastric emptying and intestinal transit, stool moves more slowly through the colon, allowing more water absorption and producing harder, less frequent bowel movements

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First, to investigate the effect of S phase on GLP-1/Notch-mediated germline proliferation, we treated wild-type and glp-1(bn18) mutants from L1 larval stage with 40 mM hydroxyurea (HU, a DNA synthesis inhibitor, (Fig

127.Matfin G, Van Brunt K, Zimmermann AG, Threlkeld R, Ignaut DA