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Roux-en-Y gastric bypass and laparoscopic gastrectomy are widely used surgical procedures for weight loss

In this study, a large portion of patients reported multiple discontinuation reasons, reflecting the multifaceted challenges involved in GLP-1 RA use including tolerability, cost, access, and individual treatment goals

The resulting global economic impact is equally striking at US$1.96 trillion in 2020, rising to over US$4 trillion in 2035 [1] (considering the cost of treating obesity and its consequences, impact on economic productivity and premature retirement or death) and demonstrates the undeniable importance of obesity from a public health perspective

Brown fat breaks down glucose, our blood sugar, and fat molecules to help maintain our body temperature by creating heat

It works through yet another mechanism entirely unrelated to GLP-1

Hence, formulation challenges have also never been greater