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Oral antidiabetic drugs were allowed if maintained at a stable dose

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158 The ability of eNAMPT to trigger this IL-6/STAT3 antiapoptotic loop was not dependent on the presence of nicotinamide (the NAMPT substrate), was not reproduced by nicotinamide mononucleotide (NMN), the product of NAMPT and was not blocked by the enzyme inhibitor FK866