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Heart Health Benefits GLP-1 medications offer impressive benefits for heart health: They lower the risk of heart attacks, strokes, and cardiovascular death They help reduce blood pressure They improve blood fat levels (like cholesterol and triglycerides) They reduce inflammation that can damage blood vessels A 2024 study using statistical modeling to compare different diabetes medications found that GLP-1 medications came out on top for reducing the risk of major heart-related events and overall death risk

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doi: 10.15277/bjd.2023.418

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These are frequently reported during dose titration periods and often decrease over time as the body adjusts

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Based on the current Phase 3 timeline, retatrutide is not expected to receive FDA approval before late 2027

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Some people also notice increased burping, mild heartburn, or a feeling of fullness that arrives earlier than usual during meals

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