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Patients should be counselled about expected side effects before starting treatment and encouraged to report any concerning symptoms to their prescriber

GLP-1 is the naturally occurring agonist for GLP-1 receptors

It works by imitating a hormone in the body called GLP-1 that stimulates insulin production and reduces appetite

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For type 2 diabetes , NICE NG28 recommends continuing GLP-1 treatment only if there is adequate response, defined as HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at 6 months

Alongside weight loss, users have reported lower blood sugar, improved energy, and better control over cravings