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[1] [2] Tirzepatide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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Acknowledgements The authors acknowledge financial support from FCT/MCTES the Portuguese Foundation for Science and Technology through project PTDC/QUI-OUT/1401/2020 and from the Associate Laboratory for Green Chemistry (LAQV), which is financed by FCT/MCTES within the scope of project UIDB/50006/2020

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