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While heavily promoted for its weight loss benefits, lawsuits argue that Wegovy caused serious gastrointestinal issues, severe dehydration, and prolonged vomiting requiring hospitalization

When we regularly take rich food, we might as well be taking sugar as carbs, exceeding our bodys caloric limit
What you dont want to do is try to DIY microdosing a GLP-1 on your own, as making changes to your dose without medical supervision may be less safe, says Kushner
This does not predict exact medication response, but can support a more nuanced discussion of individual risk

Figure 2 Consequential due to its short half-life, native GLP-1 has only limited pharmacological potential and only ~1015% of active GLP-1 is estimated to reach the general circulation (59, 6668)
7 The MT has been linked to an increased risk of depression, reportedly leading to greater food intake and less physical activity, along with increasing incidences of type 2 diabetes, anxiety, and cardiovascular disease