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10.1053/j.gastro.2011.02.018 [DOI] [PMC free article] [PubMed] [Google Scholar] 39.Butler A, Campbell-Thompson M, Gurlo T, Dawson D, Atkinson M, Butler P

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In T1D, miR-192 is elevated and controls pancreatic -cell growth by regulating cell proliferation and apoptosis, ultimately reducing insulin release

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For patients with insulin resistance or a semaglutide allergy, your doctor may suggest alternatives to GLP-1 anti-diabetic medications

A non-diabetic patient with favorable genetic predispositions in these pathways may experience more robust weight loss, while others with less favorable variants may require higher doses or longer timelines to see meaningful results