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Research has demonstrated that intentional weight loss is often associated with improvements in mood. Obesity is associated with many conditions such as chronic pain, poor mobility, social stigma, increased utilization of medical services, and sleep disturbances

10.1016/j.tem.2016.03.017 17 ChenL.YunY.GuoS.WangX.XiongM.ZhaoT.et al (2023)

You should never attempt to calculate your own equivalent dose or switch between formulations without medical supervision

Unlike many drugs, it is not metabolized by liver enzymes (such as CYP enzymes), which can reduce the risk of drug interactions

These cases allege that the manufacturers promoted the medications as revolutionary weight-loss treatments while concealing severe risks such as gastroparesis, ileus, and bowel obstruction

Some NHS trusts offer specialist weight management services for pregnant women