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Just to name 2: max cooper / jacques miller for B and T cells (yes, they havent won the Nobel), druker/lydon/sawyers for imatinib (one of the few if not the only true magic bullet for a cancer so far) Excited for the Nobel announcements

Mounjaro is approved for type 2 diabetes management, while Zepbound is approved for chronic weight management in adults with obesity or in those overweight with a weight-related health condition, such as high blood pressure, high cholesterol, or type 2 diabetes

DiMarchi (Indiana University Bloomington, USA) for helpful discussion

Thus, these in vitro findings indicate that the beneficial effect of incretin receptor agonists on fibrosis progression in MASLD patients is likely to be mediated indirectly through improvements in body weight, inflammation, and insulin resistance, rather than through the direct action on hepatic parenchymal or non-parenchymal cells

[DOI] [PubMed] [Google Scholar] 217.Williams LT, Barnes K, Ball L, Ross LJ, Sladdin I, Mitchell LJ

Zhang, K., Hooper, W., Harkness, L., & Ghassemi, A