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We used version 2 of the Cochrane risk-of-bias tool for randomised trials to assess risk of bias for the primary outcome

A new case report highlights the potential risk of "anhedonia" from high doses of tirzepatide, though it can be treated effectively.

Higher-risk patients may hold once-weekly injectable dosing for 1 week to minimize delayed gastric emptying and aspiration risk

Methods We investigated the metabolic and mechanistic effects of combining semaglutide (GLP-1RA) with Akkermansia muciniphila 11 (Akk11) in db/db mice, a model of T2D-associated MASLD

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