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Model Predictions Because of substantial log-normal within-individual variability, standard computation of reference subject simulations, as well as population predictions and weighted residuals reported by the nonlinear mixed-effects modelling software (NONMEM) are poor measures to reflect data

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Karagiannis et al

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Ethical Approval No ethics committee approval was needed as this review only summarizes findings from previously conducted studies with human participants or animals

J Clin Gastroenterol 2021;55:586-93.PubMed 111
