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GLP-1RAs can lead to weight reductions of approximately 9.6% to 17.4% of baseline body weight, which is substantially higher than what is typically achieved with lifestyle modifications alone [92,97]

Because it works in several areas of the body at once, it can have multiple helpful effects

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Their use should be considered in patients with binge-eating disorder after the remission of binge eating

Moreover, oral semaglutide improves systolic blood pressure, with superior reduction compared with placebo and sitagliptin [35, 37, 40, 42], adding an extra contribution to reduce cardiovascular risk

Drug company says safety top priority Novo Nordisk said in an email to CBC News on Friday that patient safety is of "utmost importance." "We take all reports about adverse events from use of our medicines very seriously," its statement says