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Look TM, et al

Discontinuation and reinitiation of dual-labeled glp-1 receptor agonists among us adults with overweight or obesity

The thinking is that a smaller amount of the drug can still trigger its effects, but on a more modest scale

The reduction of pro-inflammatory cytokines, improvement in intestinal barrier integrity, and potential modulation of gut microbiota composition represent mechanisms that could theoretically complement existing IBD therapies

a 25% target) at 68 weeks, well below expectations

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