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Do not inject into the inner arm, near the armpit, or too close to the elbow or shoulder joints

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GLP-1RAs: glucagon-like peptide-1 receptor agonists, BCAA: branched chain amino acids, mTOR: mammalian target of rapamycin, DXA: dual-energy X-ray absorptiometry, BIA: bioimpedance analysis Novel pharmacological approaches Besides behavioral strategies, emerging pharmacologic agents, comprising anabolic and anti-catabolic drugs, have been demonstrated to be effective in the prevention and treatment of sarcopenia or disproportionate lean mass loss in patients receiving GLP-1RAs

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The survodutide comparison is worth noting here too, as survodutide is another glucagon-containing dual agonist that shows strong liver fat effects

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Cynthia Maxwell MD, MBA, FRCSC, DABOM (Obesity Medicine), is the Medical Content Director of First Exposure, the Vice President, Medical Affairs & System Transformation and Lead Medical Executive at Womens College Hospital and Professor, Faculty of Medicine, Department of Obstetrics and Gynaecology and Division of Maternal Fetal Medicine at the University of Toronto

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Heres how these medications work: Dampens food cravings GLP-1 drugs influence the way your brain sees and responds to food

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But heres where it gets interesting: the gut microbiome plays a direct and indirect role in regulating GLP-1 secretion

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