pepcid and semaglutide PDB-101: Diabetes Mellitus: Diabetes Mellitus: undefined: Ecnoglutide vs Semaglutide: Biased GLP-1
Description
In the AMPLITUDE-O post-hoc analysis, the HR for MACE was 0.70 (95% CI 0.371.30) with baseline SGLT2is and 0.74 (95% CI 0.580.94) without SGLT2is ( P -value for interaction 0.70), and the HR for HHF was 0.23 (95% CI 0.050.97) with SGLT2is and 0.70 (95% CI 0.421.17) without SGLT2is ( P -value for interaction 0.35) [47]
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It's not clear if the participants followed diet and exercise recommendations
The investigation continues with nonischemic causes such as stress cardiomyopathy, myocarditis, pulmonary embolism, demand ischemia from sepsis, anemia, chest trauma, heart failure exacerbation, arrhythmia, and stroke
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GLP-1 receptors are present in various tissues beyond the pancreas, including the central nervous system and cardiovascular system
