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1 The two dominant incretins are glucagon-like peptide-1 (GLP-1), secreted by enteroendocrine L cells (located in the ileum and colon), and glucose-dependent insulinotropic peptide (GIP), secreted by K cells (located mainly in the duodenum)

Other effects of liraglutide are well known

Dis Models Mech 7:6371 Zhang W, Ding M-L, Zhang J-N, Qiu J-R, Shen Y-H, Ding X-Y et al (2015) mTORC1 maintains the tumorigenicity of SSEA-4 + high-grade osteosarcoma

Mediators Inflamm 2016:3094642 Kristensen SL, Rrth R, Jhund PS, Docherty KF, Sattar N, Preiss D, Kber L, Petrie MC, McMurray JJV (2019) Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials

Do I need to start at the lowest dose