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10.1039/D1FO00698C 84 LeendersF.De KoningE

Once-Weekly Dosing: Enhances convenience and compliance

Your nervous system remembers your previous weight and actively tries to return there once medication support ends

doi: 10.1016/0167-0115(83)90283-5

In a randomized controlled trial assessing the effects of butyrate in obese children, there was a consistent response which showed a significant reduction of bodyweight and waist circumference compared to placebo [4]. Per-protocol analysis in the butryate group revealed a decrease in BMI of 2.26 units and a reduction in waist circumference by 5.07cm in 6 months [4]

But, if you do experience some, it helps to remind yourself that these changes are normally reversible and dont last in the long term