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In rodent models, Sema has been shown to activate GLP-1 receptors in the hypothalamus, indirectly affecting TSH (thyroid-stimulating hormone) levels and downstream thyroid hormone regulation
Combined with diet and exercise, this can help many people lose weight

Featured Experts Rekha Kumar, MD is a board-certified endocrinologist in New York Eduardo Grunvald, MD is a board-certified internist and obesity specialist in San Diego Injectable GLP-1s: Wegovy, Zepbound and Other Weekly Shots Most GLP-1s currently approved for weight loss are administered weekly as subcutaneous injections with a prefilled pen

But, the female body needs hormonal balance of estrogen and testosterone, so GLP-1 drugs can interfere with the brains chemical messengers
