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Recent Update of Renin-Angiotensin-Aldosterone System in the Pathogenesis of Hypertension
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doi: 10.3390/medicina55060268

About 5% stopped at the lowest dose, 8% at the mid dose, and 10% at the highest dose, compared to about 3% with placebo
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Many commonly reported symptomssuch as nausea, vomiting, and constipationmatched those already known from clinical trials
