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Semaglutide has consistently demonstrated better reductions in HbA1c and body weight compared to placebo and a variety of active comparators, including sitagliptin, exenatide extended release, insulin glargine, dulaglutide, canagliflozin, and liraglutide
According to a 2024 report by the trade body UK Pet Food, 50% of dogs and 43% of cats are overweight

According to the company, Ro Body members lose an average of 15.8% of their body weight over a year with 26% of members losing even more (around 20% of their body weight)

CivicScience has data on over 170K current GLP-1 users, providing a unique lens into these medications societal, cultural, and economic impact

While genetic predisposition is just one piece of the puzzle, understanding these pathways can support a more informed discussion about whether a slower titration, lower maintenance dose, or different compounded formulation might optimize your safety and tolerability
