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Circulating ketone bodies and mortality in heart failure: A community cohort study

[DOI] [PMC free article] [PubMed] [Google Scholar] 145.Gutirrez-Cuevas J., Sandoval-Rodriguez A., Meza-Rios A., Monroy-Ramrez H.C., Galicia-Moreno M., Garca-Bauelos J., Santos A., Armendariz-Borunda J

The highest dose of oral semaglutide (14 mg) provided superior reductions in body weight compared with placebo (placebo-adjusted estimated treatment difference of 2.3 kg) (Fig

In this trial, CSF samples were taken, showing that the drug was able to cross the BBB and that 12 weeks after the trial had stopped, there was no drug present in the CSF anymore

This careful attention reduces the risk of side effects and helps optimize results

Avicenna J