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10.1016/S0021-9258(17)37366-0 3 AstrupA

The problem is the belief that the medication replaces the system

Those who are committed to a long-term approach to weight loss, with close monitoring and lifestyle changes

Potential benefits: Initial trials of semaglutide showed that the drug not only could effectively control type 2 diabetes, but also led to an average weight loss of 8 to 10 pounds

Contrave (Bupropion/Naltrexone) A combination medication that targets the brains hunger and reward pathways to help control cravings and reduce food intake, Contrave is an FDA-approved oral medication for chronic weight management that combines two active ingredients: bupropion, an antidepressant that also helps reduce appetite, and naltrexone, which is used in the treatment of alcohol and opioid dependence