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Gallbladder events have been reported at higher rates in tirzepatide users, likely related to rapid weight loss rather than a direct drug effect

The medication does not cause glycosuria

It is estimated that the medicine and associated wraparound care services will cost the NHS in England around 317.2m per year by the third year of implementation

In the case of diabetes, however, the effects that GLP-1, GIP and sugar have on the pancreas are weakened or absent

A doctor who studies the links between GLP-1 drugs and eye injuries says general practitioners should closely monitor eye health of people who start taking Zepbound

Tirzepatide targets two hormones to control appetite and blood glucose, while retatrutide targets three, potentially helping with fat burning