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6 Weight regain after stopping is predictable STEP-1 Extension and STEP-4 both show that most weight lost is regained within 612 months once the drug is discontinued

Side effects during days 1-3 are typically minimal

The maximum recommended daily dose is 100 mg of sitagliptin and 2000 mg of metformin hydrochloride (HCl)

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PMID: 30121239

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