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Other long-term considerations include gastrointestinal adaptation (most patients find side effects diminish significantly after the first 3-6 months), nutritional deficiencies that can develop with prolonged reduced caloric intake, and the psychological adjustment of maintaining a dramatically different body weight and relationship with food

This side effect stems from how these medications slow stomach emptying and alter gut bacteria fermentation patterns

Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice

Its important to follow your doctors instructions and contact them if you have any concerns

4,9,59,60 Strengths and Limitations This study has some strengths