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Some people also experience body aches , insomnia , or muscle pain on tirzepatide, though these are less common than the GI effects

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Journal of Comparative Effectiveness Research, 14 (9), e250083
[Article] [PubMed] [PMC]40

Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: a randomised, open-label phase II trial

AMPK/SIRT1 induced by semaglutide may also regulate autophagy and mitophagy, increasing transcription factor TFEB and parkin
