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Because semaglutide and other GLP-1 analogs act in the brain, when taking into account possible adverse effects during GLP-1 treatment, caution may be considered for the influence of semaglutide in the limbic system of the brain during an individualized approach

This creates variability in the quality and consistency of compounded medications, meaning theres limited or no clinical data to support their safety and effectiveness

Colonic tissue samples were collected from lesion sites (2 6 mm), fixed with 4% paraformaldehyde, embedded in paraffin, sliced (5 m thick), and stained with H&E stains as per the manufacturers protocol [24]

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