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There is evidence of androgen excess, altered glucocorticoid regulation and changes in pro-inflammatory cytokines
Regarding adverse events, one thing stands out is dysesthesia which occurred in 8.8% and 20.9% (9 mg and 12 mg, respectively) of patients, compared to 0.7% with placebo
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Compare tirzepatide and semaglutide for weight management in 2026
The main trends in these trials involve pathophysiology-based, disease-modifying therapies and the recruitment of participants in earlier stages of the disease
