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Safety Backed by Research The safety of GLP-1 medications is well-supported by extensive research

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However, several biological mechanisms and clinical observations warrant consideration

In PIONEER-4 study, oral semaglutide was non-inferior to subcutaneous liraglutide and superior to placebo in reducing HbA1c level, and superior in reducing body mass compared with both liraglutide and placebo at week 26

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Each time the tirzepatide dose increases , the body needs to readjust to stronger appetite suppression, more pronounced gastric slowing, and faster weight loss