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Assessment of saxagliptin efficacy: meta-analysis of 14 phase 2 and 3 clinical trials

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What does GIP receptor co-agonism add in preclinical models

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The clinical data suggesting a possible association come from post-marketing surveillance data that have substantial risk for bias and do not control for important confounding variables

Based on further findings, these medications might eventually complement traditional opioid use disorder (OUD) treatments like methadone or buprenorphine