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Sources and references MHRA / GOV.UK: First GLP-1 tablet for weight loss approved in the UK NHS: Overweight and obesity in adults NICE NG246: Medicines for overweight and obesity New England Journal of Medicine: Oral semaglutide 25 mg in adults with overweight or obesity European Medicines Agency: Wegovy tablets for oral use positive opinion MHRA Drug Safety Update: Semaglutide and NAION MHRA Yellow Card: report a suspected side effect MHRA / GOV.UK: GLP-1 medicines for weight loss and diabetes MHRA Products: official SmPC and patient leaflets UK prescribing decisions should follow UK regulatory information, the prescriber's clinical assessment and the official UK product information when published
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GLP-1 (glucagon-like peptide-1) is a hormone essential for appetite control and blood sugar management
The abdomen, arms, thighs, and neck develop loose, crepey skin as the underlying fat decreases
doi: 10.1093/ehjcvp/pvad080 155 SammsRJCosgroveRSniderBMFurberECDrozBABriereDAet al
doi: 10.3746/pnf.2021.26.4.367
