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GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) are two major incretin hormones that are produced in the intestine in response to food intake and stimulate insulin secretion by the -cells of the pancreas, providing up to 50-70% of insulin secretion after a meal through the so-called incretin effect

It is a relatively new drug thats been hailed a game changer by Rishi Sunak

Sources: GoodRx and CNN

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Lyophilized research-use vials are a separate, non-FDA grey-market supply

Weight loss timelines vary, but most people experience noticeable appetite reduction within 1-2 weeks and measurable weight loss within 4-6 weeks