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Finally, the insulinotropic actions of GLP-1 are preserved even in diabetic patients, although type 2 diabetes diminishes the same actions that GIP exerts in humans [30,32]

These medications have gained traction for their effectiveness in weight loss and management of type 2 diabetes

Monitor safety and risks proactively : The Veterans Affair study 1 found GLP-1 use was associated with an increased risk of 19 conditions, mainly affecting the digestive and musculoskeletal system

There are no studies or research papers that validate the product scientifically, Lemme GLP-1 Daily is an over-the-counter supplement that lacks the same level of scientific validation as prescription GLP-1 medications like Ozempic and Wegovy, she adds. Dr Vaishali Naik, an endocrinologist at Lilavati Hospital, Mumbai says, One should not use any supplements mindlessly as there is no data or proof available regarding their safety and efficacy or any side effects they can produce. She further adds that it is not known whether the supplement is extensively studied and expert-approved or recommended as safe to be used by people. Taking supplements mindlessly can lead to irreversible side effects

Large employer health benefit plans increasingly include GLP-1 medications in formularies, though typically with prior authorization requirements and step therapy protocols