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Perinatal outcomes after in-utero exposure to beta-blockers in women with heart disease: Data from the ESC EORP registry of pregnancy and cardiac disease (ROPAC)

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Association of dietary magnesium intake with chronic constipation among US adults: Evidence from the National Health and Nutrition Examination Survey

Abbreviations BBB Bloodbrain barrier CNS Central Nervous System GFAP Glial fibrillary acidic protein GLP-1R Glucagon-like peptide-1 receptor HFD Highfat diet IB4 Biotinylated isolectin B4 Iba-1 Ionized calciumbinding adaptor molecule-1 ND Normolipid diet NVU Neurovascular unit SAL Saline solution SEMA Semaglutide Author contributions VE wrote the main manuscript

Published Feb 15, 2026 8 minute read If youve lost weight with GLP-1 medications like Ozempic or Wegovy and now youre staring at loose skin, youre not alone