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The skin is a less efficient delivery route than subcutaneous fat

12 Adipose tissue expansion increases leptin levels, which regulate appetite, energy expenditure, and glucose and lipid metabolism via hypothalamic signaling

Am J Clin Nutr (2006) 83:21120

As a result of its effects on appetite and digestion, weight loss is a secondary benefit for many people who take it
The study shows that the relative risk increases are real, but the absolute number of men affected is still small

You should always seek advice from a medical professional before trying alternative approaches or medicines