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Mol Neurobiol 52:10931105

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Transitioning between GLP-1RA

Orally delivered semaglutide produces improvements in cardiovascular risk factors [8, 9], and has demonstrated potential to reduce the risk of 3-point MACE in participants with type 2 diabetes with established CVD [10]

Naltrexone/Bupropion Naltrexone is an opiate antagonist, whilst bupropion is a weak dopamine and noradrenaline reuptake inhibitor

However, the costs for these drugs may make them unavailable for those without health insurance or whose insurance will not cover the drugs for this off-label use