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doi: 10.1002/14651858.CD008650.pub2
"Participants reported drinking less, experienced fewer effects of alcohol when they did drink it, and decreased odds of binge drinking," said Alexandra DiFeliceantonio, assistant professor at Fralin Biomedical Research Institute and one of the study's co-authors
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Furthermore, the risks of myocardial infarction (HR 0.91, 95% CI 0.840.98 with GLP-1RAs and HR 0.89, 95% CI 0.800.98 with SGLT2is) and cardiovascular death (HR 0.88, 95% CI 0.800.96 with GLP-1RAs and HR 0.84, 95% CI 0.750.94 with SGLT2is) were similarly reduced in both GLP-1RA and SGLT2i groups, while the risk of stroke was reduced only with GLP-1RAs (HR 0.86, 95% CI 0.770.97 with GLP-1RAs and HR 0.97, 95% CI 0.861.10 with SGLT2is)
For patients managing multiple health conditions, these secondary benefits matter enormously
The patient has an initial BMI at or above the 95th percentile for age and sex (meeting criteria for obesity)
