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The landscape of metabolic research has been fundamentally altered by the emergence of Glucagon-Like Peptide-1 (GLP-1) analogues

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Conclusion GLP1 injections can hurt for ordinary reasons, including cold medication, wet alcohol, tense muscles, sensitive site choice, or moving too quickly through the device steps

Avgerinos I, Michailidis T, Liakos A, Karagiannis T, Matthews DR, Tsapas A, et al

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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023