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doi: 10.1007/s00394-018-1626-0

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Most patients notice decreased hunger within 3-7 days of their first injection, with more pronounced appetite suppression by week two

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Practical strategies to manage thirst include: Carrying a water bottle throughout the day as a visual reminder to drink regularly Setting hydration goals and tracking fluid intake using smartphone apps or journals Drinking small amounts frequently rather than large volumes at once, which may worsen nausea Consuming hydrating foods such as watermelon, cucumbers, and broths Limiting caffeine and alcohol, which can have diuretic effects Using appropriate oral rehydration solutions if experiencing significant gastrointestinal fluid losses (consult your healthcare provider for specific recommendations, especially with kidney disease or heart failure) Timing fluid intake strategically can help minimize discomfort

An increase in ROS production leads to lipid peroxidation, DNA damage, and protein malfunction, affecting the normal function of neurons [24,25]
