tirzepatide triple agonist G" (2/4) With we can see the benefits of dual over single incretin agonists. So what about triple agonists (GIP/GLP-1/Glucagon)βοΈ Let us introduce you to @LillyPad latest exciting molecule πLY3437943 Retatrutide vs Tirzepatide: Key Differences
Description
[1] Currently, Mounjaro is the only licensed weight loss treatment available that contains both types of receptor agonist

Monitor your blood sugar and watch out for signs of too low blood sugar such as dizziness, blurred vision, mood changes, sweating, or fast heartbeat

The decision to use tirzepatide as first-line therapy must consider factors beyond efficacy, including cost, insurance coverage, and patient preferences

Remove the cap, press the button, hold for 10 seconds
In summary, a carbon side chain of a certain length is favorable, or at least feasible, for interacting with both GLP-1 and GIPR

However, mean WL with GLP-1 RAs remains substantially lower than that achieved with BS and treatment response to GLP-1 RAs is heterogeneous
