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Overall prescribing trends The study found that 1,162,662 patients were prescribed a GLP-1 RA between January 2018 and June 2024, with 4,815,135 total prescriptions during this period

W.et al (2020)

How does the PlexusDx Precision Peptide Genetic Test help predict mood sensitivity to semaglutide

10.1016/j.neuropharm.2017.09.040 39 XuG.LiuB.SunY.DuY.SnetselaarL

Until more research is available, the use of these drugs in T1D should be done carefully, with a thorough discussion with patients about potential risks and benefits of this approach

Remarkably, the first GLP-1R agonist approved for clinical use was exenatide (synthetic exendin-4), a peptide originally isolated from Heloderma suspectum lizard venom by John Eng in 1992 (72)