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Description
Over the 20th century, additional treatments were developed and FDA approved for treatment of overweight and obesity, including phentermine, phentermine/topiramate, orlistat, and naltrexone/bupropion
But several aspects deserve scrutiny, and we will address them throughout this review
CMH: data analysis and interpretation, statistical analysis, critical revision of the manuscript for important intellectual content

And prescribers should continue to carefully weigh the benefits and risks of using weight loss products in patients with a history of suicide attempts or act of self-harm
The journey began in the 1960s with the formulation of the incretin hypothesis, which proposed that intestinal hormones stimulate insulin secretion

NN : Several anti-obesity medications, also known as AOMs, have been approved for chronic weight management and continue to be used successfully